The Sonotherapy system interfaces with the patient through sensors to monitor ECG (electro-cardiogram) activity normally at four points. These four points are attached to the patient's forearms and legs while three temperature sensors on each foot monitors skin temperatures over arteries and one sensor monitors the ambient temperature. All monitors are in real time. The computer program analyses and characterizes the EGC waveforms (Qd, P+, P , Q, R, R', S, ST, T+, T-), and combines them with the temperature readings and past treatment data to determine the most suitable sound waveform for the current treatment. Therefore, not only tailoring treatment to your body but also basing it on previous treatment results.

The computer then produces sound impulses from the transducers in sync with the systolic phase of your heart beat. These sound impulses enter the body through the soles of your feet, from where they propagate throughout the whole body. More frequently than not, the sound level, is so low that you will not hear the sound impulses. This low energy sound level is one of the reasons that Sonotherapy is safe and without side-effects.